Sweden-based Nolato, a global provider of injection molded parts for numerous industrial and medical applications has developed Nolava as a collaborative project with companies including Altair and Avalon Innovation. Nolava is Nolato’s medical self-injector, a complex electro-mechanical device housed in an injection molded fiber-reinforced plastic body. Within this presentation different aspects of the product design cycle are considered, including co-simulations of the device operation during the actual injection process, misuse in case of forceful bending or opening of the loading tray, and drop tests of the autoinjector. Based on Altair’s optimization technology, alternatives for the rib structure of the casing are investigated. To assure manufacturability, molding and assembly simulations are performed to identify and mitigate problems likely to occur throughout the process.